Here are weights I'm going by for each dps tree and possible BiS.
http://elitistjerks.com/f72/t55505-opti ... is_thread/
Keep in mind Frost weights may be off, also look at the post from Kaejin for you blood dpsr's so as to keep your hit/exp caps and not have to shuffle gear around when Voldrethar drops.
Play around with a char planner such as:
to ensure you are at 8% melee hit (or around 11-13% spell hit for unholy) and 26 Expertise.